March 23, 2006 Mail Stop 4561 VIA U.S. MAIL AND FAX (703) 287-5901 Harry Brill Chief Financial Officer Gladstone Commercial Corporation 1521 Westbranch Drive Suite 200 Mclean, VA 22102 Re: Gladstone Commercial Corporation Form 10-K for the year ended December 31, 2005 Filed March 28, 2006 File No. 0-50363 Dear Mr. Brill: We have completed our review of your Form 10-K and related filings and do not, at this time, have any further comments. Sincerely, Daniel L. Gordon Accounting Branch Chief